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. Author manuscript; available in PMC: 2012 Sep 15.
Published in final edited form as: J Immunol. 2011 Aug 10;187(6):3087–3095. doi: 10.4049/jimmunol.1003879

FIGURE 7. DR5 cross-linking did not inhibit DC cross-priming of soluble OVA and OVA-coupled latex beads.

FIGURE 7

(A) CD11c+ BM-DCs (5 × 105) were cultured in control mAbs or anti-DR5 mAbs-coated 24-well plates or in control wells (PBS). The cells (2 × 104) were then cocultured for 2.5 days with indicated dose of soluble OVA protein and CFSE-labeled OT-I T cells (5 × 104). (B) OVA-coupled beads were cocultured for 4 days with the DCs and CFSE-labeled OT-I T cells. Numbers represent percentage of proliferating CD8β+ T cells. Cumulative data from two independent experiments are shown as mean ± SEM.