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. Author manuscript; available in PMC: 2012 Oct 1.
Published in final edited form as: J Steroid Biochem Mol Biol. 2011 Apr 13;127(1-2):74–82. doi: 10.1016/j.jsbmb.2011.04.004

Figure 1.

Figure 1

Domain structure of the androgen receptor. The androgen receptor is composed of a N-terminal domain (NTD) or A/B domain, with transactivation function mediated through the AF-1 region, a DNA-binding (DBD) or C domain, harboring two zinc finders that recognize AREs in regulated genes, a hinge region or D domain, and a ligand-binding (LBD) or E domain that contains the steroid binding pocket and helices 11 and 12 as well as the activation function-2 region (AF-2).