Figure 1. Naïve B cell access to the outer follicle is promoted by EBI2.

(A) Isolated lymphoid follicles in the small intestine of 50:50 mixed WT or EBI2-/- Igh^b (red) and WT Igh^a (green) BM chimeras, stained as indicated. (B) Spleen and pLN sections from WT or EBI2 deficient mice that had received one day transfers of WT (Igh^a) B cells. Stained to detect the transferred B cells (IgM^aD^a, blue) and endogenous B cells (B220, brown). F, follicle (a single follicle is labeled); IF, inter follicular region; OF, outer follicle; T, T zone; MZ, marginal zone.