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. Author manuscript; available in PMC: 2012 Sep 15.
Published in final edited form as: J Immunol. 2011 Aug 15;187(6):3026–3032. doi: 10.4049/jimmunol.1101262

Figure 3. EBI2 functions together with CCR7 and CXCR5 to distribute activated B cells along the B-T boundary.

Figure 3

(A) Distribution of WT and EBI2 KO MD4 B cells in CCR7-ligand deficient (plt/plt) recipient spleens at 0 or 6 h after HEL antigen injection. (B) Distribution of EBI2 het CXCR5 KO and EBI2 CXCR5 DKO MD4 B cells in the spleen of WT hosts 6 h after HEL antigen injection. Transferred MD4 B cells were detected by staining for IgMa and IgDa (blue) and endogenous B cells with antibodies to total IgD (brown). Views are representative of three mice.

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