Figure 6. EBI2-dependent migration response of day 2 activated B cells.
(A) Migration of day 2 activated WT and EBI2 KO MD4 B cells, and endogenous B cells, to spleen extract (sp) or medium alone (nil). Data are from two mice. (B) Migration of WT and EBI2 KO MD4 B cells activated by exposure to HEL antigen and in vitro culture with anti-CD40 to spleen extracts from WT (left panel) and CXCL13-deficient (right panel) mice (**P<0.01, unpaired, two-tailed Student's t-test).