Table 2.

mtDNA copy number levels by selected characteristics

		Controls
Characteristic	N	Mean	25%	Median	75%	p-value
Smoking status
Never	286	1.13	0.88	1.07	1.28
Ever	13	1.02	0.83	0.96	1.36	0.54
Alcohol use
Never	293	1.12	0.88	1.06	1.28
Ever	6	1.41	0.95	1.38	1.53	0.23
Body mass index (kg/m2)
<25 kg/m2	186	1.15	0.90	1.08	1.30
≥25 and <30 kg/m2	97	1.08	0.84	1.04	1.23
≥ 30 kg/m2	16	1.09	0.90	1.01	1.36	0.39
Regular moderate or vigorous physical activity
≤ 3 MET h/day	97	1.12	0.86	1.05	1.27
>3 MET h/day	31	1.08	0.92	1.01	1.21	0.58
Family history of gastric cancer
No	280	1.13	0.88	1.06	1.29
Yes	19	1.13	0.97	1.08	1.39	0.45
NSAID use, within past year
No	292	1.12	0.88	1.06	1.29
Yes	7	1.23	1.05	1.16	1.30	0.27
Regular multiple vitamin use
No	277	1.13	0.88	1.06	1.28
Yes	22	1.11	0.91	1.16	1.31	0.78
H.pylori positive *
No	18	1.10	0.76	1.04	1.28
Yes	226	1.16	0.90	1.12	1.33	0.28
Age at baseline, years
<50	68	1.16	0.89	1.10	1.36
50–60	70	1.19	0.86	1.16	1.34
>60	161	1.08	0.87	1.02	1.23	0.14
Fruits/vegetables intake, g/d
<median	149	1.12	0.87	1.03	1.25
≥ median	150	1.13	0.89	1.08	1.31	0.39

P-value comparing mtDNA copy number between different levels of characteristic (Anova and wilcoxon)

^*H. pylori status available on 244 controls only