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. 2011 Mar 31;18(9):898–909. doi: 10.1038/gt.2011.37

Figure 1.

Figure 1

Characterization of adenovirus (Ad) vectors used in this work. (a) Schematic representations of the IL-12 or IL-18 gene inserted into the E3 region of RdB, respectively. RdB/IL-12/IL-18 is comprised of the IL-12 and IL-18 genes in the E1 and E3 region of RdB, respectively (asterisk indicates mutation at Rb binding site of E1A). (b, c) Expression of IL-12 (b) and IL-18 (c). The concentration of cytokines was measured in the culture supernatants 96 h after infection by ELISA. Mean values and s.e.m. of three or more experiments, each performed in triplicate, are shown.