Figure 5.

The High Density of Variants Determined by Whole-Genome Sequence Data Permits Full-Genome Haplotyping

(A) Haplotypes of all the autosomes for the four children of pedigree A. Blue and orange shades represent the two paternal and maternal chromosomes, respectively; dark and light shades represent segments inherited from the corresponding grandfather or grandmother, respectively.

(B) Expanded view of chromosome 1 showing the density of variants supporting the meiotic origins of each haplotype. Red, blue, magenta, and green represent regions inherited from the paternal grandfather, paternal grandmother, maternal grandfather, and maternal grandmother, respectively. The height of the gray bracket to the right of each graph corresponds to 1000 variants/Mb.