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. 2011 Sep 9;89(3):354–367. doi: 10.1016/j.ajhg.2011.07.015

Table 3.

Type I Errora and Power of Fixed-Threshold and VT Methods

n α Asymptotic
Permutation
T1 T5 VT T1 T5 VT Priceb
H0 : βj = 0
500 10−2 0.91 0.96 0.84 0.62 0.72 0.90 0.88
10−3 0.79 0.85 0.57 0.54 0.61 0.83 0.83
1000 10−2 0.96 0.99 0.86 0.73 0.81 0.93 0.93
10−3 0.88 0.90 0.66 0.68 0.70 0.89 0.88
H1 : β1 = … = β10 = x, β11 = 0
500 10−2 0.39 0.59 0.66 0.34 0.55 0.67 0.67
10−3 0.15 0.29 0.36 0.13 0.27 0.40 0.39
1000 10−2 0.50 0.61 0.68 0.46 0.58 0.69 0.69
10−3 0.23 0.33 0.40 0.21 0.30 0.43 0.43
H1 : β1 = … = β11 = x
500 10−2 0.29 0.82 0.71 0.25 0.80 0.72 0.71
10−3 0.10 0.57 0.42 0.09 0.54 0.46 0.45
1000 10−2 0.35 0.82 0.68 0.32 0.81 0.69 0.68
10−3 0.13 0.57 0.41 0.12 0.54 0.44 0.42
a

Divided by α.

b

VT method of Price et al.9