| Initial treatment | Rescue therapy | |
| tenofovir | → | add-on entecavir |
| lamivudine | → | add-on tenofovir |
| adefovir | → | add-on entecavir |
| entecavir | → | add-on tenofovir |
| telbivudine | → | add-on tenofovir |
| pegylated interferon | → | switch to entecavir or tenofovir |
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