Table 1.
Input data of the base case scenario
| Variable | Value | Reference | ||
|---|---|---|---|---|
| HBeAg-positive | 20.00% | 8 | ||
| Chronic infection | 92.70% | 7 | ||
| Cirrhosis | 7.30% | |||
| Transition probabilities | Annual rates of events according to HBeAg | |||
| Positive | Negative | |||
| Chronic hepatitis B | Spontaneous resolution | 6.90% | 1.60% | 9 |
| Compensated cirrhosis | 3.00% | 4.60% | ||
| Hepatocellular carcinoma | 1.50% | 1.50% | ||
| Compensated cirrhosis | Decompensated cirrhosis | 7.30% | 7.30% | 9 |
| Hepatocellular carcinoma | 3.40% | 3.40% | ||
| Death | 4.90% | 4.90% | ||
| Decompensated cirrhosis | Liver transplantation | 21.00% | 21.00% | 9 |
| Death | 19.00% | 19.00% | ||
| Hepatocellular carcinoma | Liver transplantation | 25.00% | 25.00% | 9 |
| Death | 43.30% | 43.30% | ||
| Liver transplantation | Death | 6.90% | 6.90% | 9 |
Abbreviation: HBeAg, hepatitis B e antigen.