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. Author manuscript; available in PMC: 2011 Sep 9.
Published in final edited form as: J Immunol. 2010 Mar 10;184(8):4378–4390. doi: 10.4049/jimmunol.0903416

FIGURE 6.

FIGURE 6

T. gondii -associated liver pathology and control of chronic infection are not altered inil22−/− mice. Micewere infected with T. gondii (ME49 strain) as in Fig. 5. One of two experiments, with five mice per group, is shown. Data are shown as mean ± SEM (A, C–E). A, Expression of iNOS, TNF-α, and IL-10 mRNA in liver of 30-d T. gondii-infected mice. B, H&E-stained liver section taken from WT and il22−/− mice infected for 30 d (×20 magnification). C, Liver lesion frequency, percentage of lymphocytes, and percentage of macrophages. D, T. gondii cyst frequency in brain tissue infected for 120 d. E, Brain pathology with meningitis and peri-vascular inflammation score. F, Brain-infiltrating lymphocytes stained for CD4, TNF-α, and IFN-γ.