Table 2.

Studies included in systematic review for calculating the diagnostic efficiency statistics

Studies	Test	Morphological criteria	Gold Standard	Number of blastomeres analyzed	Chromosomes analyzed by FISH	TP	FP	FN	TN
Baltaci et al. [92]	Morphology	Veeck et al. [98]	FISH	1	X, Y, 13, 18, 21	150	115	274	437
Magli et al. [93]	Morphology	Alikani et al. [99]	FISH	1	X, Y, 13, 15, 16, 18, 21, 22	2978	1106	531	490
Munné et al. [94]	Morphology	cell number, fragmentation degree, blastomere sized	FISH	1	X, Y, 13, 16, 15, 17, 18, 21, 22,	1832	651	2401	1170
Rubio et al. [95]	Morphology	Alikani et al. [99]	FISH	1 or 2	X, Y, 13, 15, 16, 18, 21, 22	1895	762	1417	1637
Ziebe et al. [96]	Morphology	cell number, fragmentation degree and location, blastomere sized, cytoplasmic appearance	FISH	Every blastomere	X, Y, 13, 16, 18, 21, 22	41	34	7	21
Wilton et al. [46]	PGS-FISH	Not reported	CGH	1	X, Y, 13, 16, 18, 21, 22	29.5	0.5	19.5	50.5
Keskintepe et al. [97]	PGS-FISH	Not reported	CGH	1	X, Y, 17, 16, 18, 21, 22	32.5	0.5	10.5	2.5
Daphnis et al. [52]	PGS-FISH	Not reported	CGH	1 or 2	X, Y, 18 allways 3, 4, 6, 10, 11, 13, 16, 18, 22	17.5	0.5	10.5	3.5

TP True positive; FP False positive; FN False negative; TN True negative