Table 1.
Cases included in GTNI study cohort listed with patient age at first diagnosis, sex, histopathological grade (Grade), Sequenom® genotyping result (Sequenom) and IHC for IDH1 R132H (R132H IHC)
| Case | Age | Sex | Grade | Sequenom | R132H IHC |
|---|---|---|---|---|---|
| 1 | 70 | M | LG | R132H | NA |
| 2a | 40 | M | HG: MVP/NEC | R132H | NA |
| 3a | 57 | M | LG | R132H | NA |
| 4a | 56 | M | HG | R132H | NA |
| 5a | 40 | M | LG | R132H | + |
| 6a | 38 | M | LG | R132H | + |
| 7a | 47 | M | LG | R132H | + |
| 8 | 43 | F | LG | R132H | NA |
| 9 | 40 | M | HG | NA | + |
| 10a | 41 | M | LG | R132H | + |
| 11 | 53 | F | HG | NA | + |
| 12 | 29 | F | HG | R132H | + |
M male, F female, LG low-grade, HG high-grade, MVP microvascular proliferation, NEC necrosis, R132H IDH1 R132H mutation
aCases included in a previous study of 1p/19q co-deletion in GTNI [3]