Table 3.

The effects of a high‐fructose diet on adipocyte hormones in rhesus monkeys.

	Monkeys with metabolic syndrome				Monkeys with diabetes
Measurement	n	Time	Result	Δ%	n	Time	Result	Δ%
Total adiponectin (μg/mL)	23	Baseline	7.12 ± 0.95		4	Baseline	5.44 ± 0.97
		6 months	5.06 ± 0.74	−27%c		6 months	4.47 ± 0.02	−18%
		12 months	5.05 ± 0.64	−28%c		12 months	3.17 ± 1.00	−42%
HMW adiponectin (μg/mL)	25	Baseline	2.25 ± 0.34		4	Baseline	1.63 ± 0.51
		6 months	1.31 ± 0.22	−44%c		6 months	0.88 ± 0.35	−46%
		12 months	1.23 ± 0.19	−47%c		12 months	0.96 ± 0.38	−41%
HMW/Total adiponectin	25	Baseline	0.281 ± 0.016		4	Baseline	0.270 ± 0.060
		6 months	0.237 ± 0.017	−16%b		6 months	0.320 ± 0.036	+18%
		12 months	0.224 ± 0.015	−20%c		12 months	0.252 ± 0.058	−7%
Leptin (ng/mL)	25	Baseline	8.96 ± 0.89		4	Baseline	9.75 ± 1.53
		6 months	12.53 ± 1.05	+40%c		6 months	11.74 ± 2.42	+20%
		12 months	12.77 ± 0.86	+42%c		12 months	9.10 ± 2.32	−7%

Mean ± SEM.

^ap ≤ 0.05; ^bp ≤ 0.01; ^cp ≤ 0.001.

Abbreviations: HMW, high molecular weight.