Figure 3.

SWI/SNF remodeling activity can be targeted by a transcriptional activator. (A) Schematic of nucleosomal array templates. (B) The ³²P-labeled arrays (0.2 nm final) were mixed with unlabeled arrays (3 nm final) in the four possible combinations and then either incubated with HincII alone (○) or exposed to 0.8 nm SWI/SNF and HincII in the absence (crossed circles), or presence of 10 nm GAL4–VP16 (●). The digestion of the labeled array with time was quantified and graphed at left.