Table 1.

RoPE Database

Database	# of subjects	# w/PFO	# w/o PFO	RoPE Investigator
APRIS [6]	83	17	66	Marco DiTullio
Bern (published) [30]	159	159	-	Krassen Nedeltchev
Bern (unpublished)	249	249	-	Heinrich Mattle
CODICIA [31]	486	266	240	Joaquin Serena
PFO-ASA Study [5]	581	267	314	Jean-Louis Mas
German Study [24]	1126	389	737	Christian Weimar
Lausanne	172	93	79	Patrik Michel
NOMASS [32]	60	23	37	Mitchell Elkind
PICSS [33]	250	98	152	Shunichi Homma
Sapienza (unpublished)	343	133	210	Emanuele Di Angelantonio
				Federica Papetti
Toronto [34]	114	114	-	Cheryl Jaigobin
Tufts	140	140	-	David Thaler
Total Estimates*	2546	1484	1062