Table 1.
Effects of ACC lesions on the anti-nociceptive effects of EA in rats with formalin injection
| Paw lifting time (s) | Paw licking time (s) | |||
|---|---|---|---|---|
| Phase 1 | Phase 2 | Phase 1 | Phase 2 | |
| Formalin to left paws | ||||
| Sham lesion | 66.3 ± 13.9 | 595.5 ± 80.0 | 61.3 ± 12.2 | 440.1 ± 44.7 |
| Sham lesion + ipsi-EA | 45.8 ± 8.0 | 282.7 ± 28.7 *** | 56.1 ± 6.3 | 378.3 ± 48.2 |
| Sham lesion + contra-EA | 65.3 ± 10.5 | 369.7 ± 59.8 ** | 47.0 ± 9.1 | 231.3 ± 30.6 *** |
| ACC lesion | 63.1 ± 8.1 | 623.6 ± 80.9 | 45.0 ± 8.2 | 362.6 ± 60.9 |
| ACC lesion + ipsi-EA | 42.3 ± 6.4 | 401.7 ± 53.1 ** | 53.0 ± 5.4 | 357.9 ± 56.8 |
| ACC lesion + contra-EA | 57.3 ± 3.2 | 496.9 ± 68.2 | 68.5 ± 9.2 | 358.8 ± 36.0# |
| Formalin to right paws | ||||
| Sham lesion | 115.6 ± 19.2 | 815.5 ± 104.4 | 61.5 ± 4.7 | 269.6 ± 48.4 |
| Sham lesion + ipsi-EA | 81.0 ± 11.9 | 365.1 ± 50.9 *** | 63.0 ± 7.2 | 249.1 ± 42.7 |
| Sham lesion + contra-EA | 104.7 ± 16.4 | 494.0 ± 101.1 *** | 51.4 ± 7.5 | 140.1 ± 39.2 ** |
| ACC lesion | 107.7 ± 11.5 | 854.1 ± 88.1 | 58.1 ± 7.9 | 205.3 ± 39.0 |
| ACC lesion + ipsi-EA | 71.0 ± 10.5 | 395.9 ± 39.2 *** | 65.1 ± 7.1 | 180.7 ± 45.9 |
| ACC lesion + contra-EA | 91.3 ± 12.6 | 939.2 ± 92.6 | 61.7 ± 5.9 | 246.7 ± 56.3 |
* p < 0.05; ** p < 0.01; *** p < 0.001, compared with the formalin group of the corresponding lesion type (sham lesion or ACC lesion). # p < 0.05, compared with the formalin + contralateral EA group of sham lesions.