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. 2011 Sep 9;6(9):e24366. doi: 10.1371/journal.pone.0024366

Table 2. Dissociation constants for human AZ-ODC and AZ-AZI complexes.

AZ peptide K d,AZ-ODC (µM) K d,AZ-AZI (µM)
WT 0.71 ± 0.005 0.027 ± 0.0001
87-124 12.7 ± 0.28 0.16 ± 0.001
95-228 1.5 ± 0.01 0.024 ± 0.0002
95-176 5.6 ± 0.04 0.06 ± 0.004
95-135 10.3 ± 0.07 ND
95-124 18.6 ± 0.13 0.28 ± 0.002
100-228 5.3 ± 0.03 0.068 ± 0.0007
100-176 10.8 ± 0.07 ND

The dissociation constants (K d) of AZ-ODC and AZ-AZI were derived from global fitting of the sedimentation velocity data to the model of A+B↔AB hetero-association in the SEDTHAT program.