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. Author manuscript; available in PMC: 2012 Oct 1.
Published in final edited form as: Allergy. 2011 May 24;66(10):1304–1311. doi: 10.1111/j.1398-9995.2011.02647.x

Figure 5.

Figure 5

LTD4 augments LTB4 induced chemotaxis of monocytes. (A) Chemotactic activity of monocytes to different concentrations of or LTB4, LTD4 or LTB4 and LTD4 (100 nmol/L) in the presence or absence of MK571 (MK; 100 nmol/L). *p < 0.05 for LTB4+LTD4 comparred to LTB4 alone. #p<0.05 for LTB4+LTD4 comparred to LTB4+LTD4 plus MK571. (B) Cells were preincubated with different concentrations of CP105695 for 20 min and stimulated with LTB4 (10 nmol/L). #p<0.05 for LTB4 comparred to LTB4 plus CP105696. (C) Cells were preincubated with pertussis toxin (100 ng/mL) overnight and stimulated with LTB4 (10 nmol/L), LTD4 (100 nml/L) or LTB4 and LTD4. *p < 0.05 for agonist(s) plus Ptx comparred to agonist(s) alone. +p<0.05 comparing LTB4 and LTD4 to LTB4 alone. Data from 3 different donors are presented as the migration index in comparison with vehicle control (mean ±SD).