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DNA damage sensitivity in T. brucei RAD51 and RAD51 paralogue mutants. A. The concentration of phleomycin that caused 50% growth inhibition (IC50) of wild-type (wt) cells is compared with two (1, 2) independent heterozygous (+/−) and homozygous (−/−) mutants of RAD51-4 and RAD51-6. B. Comparison of the phleomycin IC50s of wt, rad51−/−, rad51-3−/−, rad51-4−/−, rad51-5−/− and rad51-6−/− cells. Values are averages from at least three experiments; bars indicate standard deviation.
