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. Author manuscript; available in PMC: 2011 Oct 1.
Published in final edited form as: Arterioscler Thromb Vasc Biol. 2010 Jul 15;30(10):2022–2031. doi: 10.1161/ATVBAHA.110.210849

Figure 1.

Figure 1

A through D, SU6656 or toxin B only partially inhibits macrophage LDL uptake and cholesterol accumulation. Macrophages were incubated for 24 hours with 250 µg/mL 125I-LDL and the indicated addition (A and C) or 1 mg/mL LDL and the indicated addition (B and D). 125I-LDL uptake is the sum of cell-associated and degraded 125I-LDL. To determine basal macrophage cholesterol levels, macrophages were also incubated for 24 hours without LDL addition. *P< 0.05 for LDL vs LDL plus added inhibitor.