Table 4.
Performance of procalcitonin for detecting patients with bacterial infection at various cutoff values (± 95%CI)
PCT (ng/ml) | PCT > 0.5 | PCT > 1.35 | PCT > 2 | PCT > 5 |
---|---|---|---|---|
Bacterial infection prevalence = 48.7% | ||||
Sensitivity | 1.00 ± 0.00 | 0.81 ± 0.11 | 0.67 ± 0.12 | 0.50 ± 0.13 |
Specificity | 0.63 ± 0.12 | 0.77 ± 0.11 | 0.82 ± 0.08 | 0.90 ± 0.08 |
Positive predictive value | 0.72 ± 0.06 | 0.77 ± 0.10 | 0.78 ± 0.08 | 0.83 ± 0.15 |
Negative predictive value | 1.00 ± 0.00 | 0.81 ± 0.11 | 0.72 ± 0.08 | 0.65 ± 0.08 |
Positive likelihood ratio | 2.70 | 3.52 | 3.72 | 5.00 |
Negative likelihood ratio | 0.00 | 0.25 | 0.40 | 0.56 |
Younden's index | 0.63 | 0.58 | 0.49 | 0.40 |