Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
A schematic illustration of the design of a peptide-linked molecular beacon and its delivery into cell nucleus. The NLS peptide is covalently linked to the molecular beacon using a modified nucleotide (dT-C6-NH2) in its quencher arm. The NLS linked molecular beacons are delivered into the cytoplasm first using a reversible membrane permeabilization agent Streptolysin O (SLO), and the NLS peptide actively transports the probes into the nucleus of a living cell.
