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. Author manuscript; available in PMC: 2011 Sep 11.
Published in final edited form as: Bioconjug Chem. 2008 Nov 19;19(11):2205–2211. doi: 10.1021/bc800322a

Figure 3.

Figure 3

Efficiency of nuclear delivery of NLS linked MB probes in living cells. (a) Fluorescence images of unquenched probes delivered to the cytoplasm of living cells using SLO. The NLS-conjugated probes show a much higher signal level in cell nucleus as compared with probes without the NLS peptide. (b) Quantification of nuclear delivery efficiency of probes with and without NLS peptide. The average fluorescence signal from NLS-conjugated probes in cell nucleus has a ~3.3 fold increase compared with probes without NLS peptide.