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Histopathology of IgG4-related sclerosing cholangitis. The surgical specimens show diffuse inflammatory cell infiltration with fibrosis involving peribiliary glands (a), obliterative phlebitis (b), and infiltration of many IgG4+ plasma cells (c). The liver needle biopsy reveals portal inflammation (d), bile duct damage (e), and IgG4+ plasma cells (f).
