Skip to main content
. Author manuscript; available in PMC: 2012 Sep 2.
Published in final edited form as: J Proteome Res. 2011 Jul 28;10(9):4120–4133. doi: 10.1021/pr200310s

Figure 3.

Figure 3

Genetic background-dependent changes in taurine excretion. Depletion of urinary taurine excretion in (A) wild-type and (B) Ppara-null mice on the B6 background in response to chronic alcohol consumption. Elevation in urinary taurine excretion in (C) wild-type and (D) Ppara-null mice on the 129S background in response to chronic alcohol consumption. Dotted and solid lines represent the variation in the urinary excretion of taurine in control and alcohol diet-fed mice of the respective genotypes and backgrounds. One-way ANOVA with Bonferroni's correction for multiple comparisons was used to estimate statistical significance of the variation of the metabolites on alcohol-treatment within same background. ‡, significantly different (P < 0.05) from the Ppara-null mice of same treatment group; #, significantly different (P < 0.05) from control mice of same genotype and *, significantly different (P < 0.05) from alcohol-treated wild-type mice.