Table 2. List of Background-independent Metabolites for Chronic Alcohol Exposure in Ppara-null Mice.
| Marker | RTb | m/z | Trend | Identity | Possible Origin |
|---|---|---|---|---|---|
| N1 a | 0.6 | 221.066 | ↑ | Ethyl-β-D-glucuronide | Alcohol metabolism |
| N1a | 0.6 | 203.056 | ↑ | (N1-H2O) | Alcohol metabolism |
| N1b | 0.6 | 341.017 | ↑ | (N1+2HCO2H+CO) | Alcohol metabolism |
| N2 | 0.9 | 116.035 | ↑ | N-acetylglycine | Alcohol metabolism |
| N3 | 3.7 | 204.066 | ↑ | Indole-3-lactic acid | Tryptophan Metabolism |
| N17 | 3.3 | 165.055 | ↑ | Phenyllactic acid | Phenylalanine metabolism |
| P1 | 0.6 | 245.063 | ↑ | Ethyl-β-D-glucuronide + Na+ | Alcohol metabolism |
| P1a | 0.6 | 199.023 | ↑ | (P1-HCO2H) | Alcohol metabolism |
| P1b | 0.6 | 181.013 | ↑ | (P1-HCO2H-H2O) | Alcohol metabolism |
| P1c | 0.6 | 159.03 | ↑ | (P1-HCO2H-H2O-Na+ +H+) | Alcohol metabolism |
| P2 | 3.7 | 206.081 | ↑ | Indole-3-lactic acid | Tryptophan Metabolism |
| P2a | 3.7 | 188.071 | ↑ | P2-H2O | Tryptophan Metabolism |
| P2b | 3.7 | 160.076 | ↑ | P2-HCO2H | Tryptophan Metabolism |
a
‘N’ indicates marker detected in negative mode and ‘P’ indicates marker detected in positive mode.
b
RT (retention time) in minutes.