Skip to main content
. Author manuscript; available in PMC: 2012 Sep 30.
Published in final edited form as: Tetrahedron. 2011 Sep 30;67(39):7461–7469. doi: 10.1016/j.tet.2011.07.064

Table 6.

Iodination of 3-chlorotoluene (1i) using different iodination reagents.*

graphic file with name nihms315974u6.jpg
Entry Reaction Conditionsa Reaction time (h) Conversion (%) Yield
2i (%) 3i (%) 4i (%)
6-1 Ag2SO4, I2, DCM 16 10 - 2 8
6-2 AgSbF6, I2, DCM 16 100 3 7 >90
6-3 AgBF4, I2, DCM 16 100 3 8 70
6-4 AgPF6, I2, DCM 16 100 3 15 80
*

Percent conversion and yields were determined by GC-MS;

a

one equivalent (eq.) of each reagent was employed.