Table 1.
Sample characteristics (n=2,930)
| Original cohort (n=1,046) |
Offspring cohort (n=1,884) |
|
|---|---|---|
| Age, years | 76±6 | 60±9 |
| Women | 658 (63%) | 997 (53%) |
| Winter season | 361 (35%) | 799 (42%) |
| Smoking | 134 (13%) | 262 (14%) |
| Body mass index, kg/m2 | 26.7±4.6 | 28.1±5.2 |
| Systolic blood pressure, | 146±22 | 128±19 |
| mmHg | ||
| Hypertension | 808 (77%) | 796 (42%) |
| Antihypertensive therapy | 551 (53%) | 571 (30%) |
| History of heart failure | 32 (3%) | 13 (0.7%) |
| History of myocardial | 105 (10%) | 72 (4%) |
| Infarction | ||
| Cardiac murmur | 273 (26%) | 253 (13%) |
| PR-interval, ms | 170±32 | 162±24 |
| 25(OH)D, ng/mL* | 29.2±12.6 | 19.6±7.4 |
| Betablockers | 183 (18%) | 113 (13%) |
| Angiotensin converting | 79 (8%) | 252 (13%) |
| enzyme inhibitors | ||
| Cholesterol lowering drugs | 44 (4%) | 322 (17%) |
Values are shown as mean ± SD, or n (%).
Serum 25(OH)D was determined by a competitive protein-binding assay in the Original Cohort, and a radioimmunoassay in the Offspring Cohort. Due the use of different assays, serum concentrations cannot be directly compared between cohorts; standardized values were used in the regression analyses.