Table 2.
Risk of incident atrial fibrillation: results of Cox regression analyses with 25(OH)D as standardized continuous variable and dichotomized at the cohort specific 20th percentile
| Hazards ratio* (95% confidence interval) |
p value | |
|---|---|---|
| 25(OH)D as standardized continuous variable | ||
| Age- and sex-adjusted | 0.97 (0.88 – 1.07) | 0.49 |
| Main model† | 0.99 (0.89 – 1.10) | 0.82 |
| Main model + hypertension, history of MI, history of HF, and winter season | 0.99 (0.88 – 1.10) | 0.81 |
| 25(OH)D < the cohort specific 20th percentile | ||
| Age- and sex-adjusted | 1.08 (0.84 – 1.39) | 0.54 |
| Main model† | 1.06 (0.82 – 1.38) | 0.65 |
| Main model + hypertension, history of MI, history of HF, and winter season | 1.08 (0.82 – 1.41) | 0.59 |
MI, myocardial infarction; HF, heart failure.
Hazards ratios for incident AF are shown per cohort-specific 1 SD increment in 25(OH)D levels or for presence of a 25(OH)D concentration < the cohort specific 20th percentile.
The main model covariates included: age, sex, body mass index, PR-interval, and cardiac murmur.