Table 1.

Tsg affinity for BMP2 varies depending on host source.

Ligand	kon [M−1s−1]	koff [s−1]	KD [nM]
xTsg from insect cells	11 ± 0.8 × 104	2.0 ± 0.5 × 10−4	2.5
xTsg from E. coli	3.8 ± 1 × 104	7.1 ± 0.5 × 10−4	20.2
mTWSG from E. coli	4.4 ± 0.3 × 104 (10.7 ± 3 × 104)a	7.6 ± 1.3 × 10−4 (2.0 ± 0.3 × 10−2)	39.6 (301)

^aValues in parenthesis denote low affinity interaction of the biphasic interaction between mTWSG1 and BMP2.