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. 2011 Mar 9;31(8):1743–1750. doi: 10.1038/jcbfm.2011.23

Figure 1.

Figure 1

Characterization of ischemic lesion with multiparametric perfusion, diffusion, and pH-weighted APT MRI of a representative acute stroke animal with MCAO. The animal showed a large perfusion and diffusion lesion mismatch, whereas the pH-weighted APT lesion agreed reasonably well with the diffusion deficit. ADC, apparent diffusion coefficient; APT, amide proton transfer; CBF, cerebral blood flow; CESTRasym, chemical exchange saturation transfer ratio asymmetry; MCAO, middle cerebral artery occlusion; MRI, magnetic resonance imaging.