Table 5. Odds ratio (OR) of each genotype combination of IL6 rs10242595 and MPO rs8178406 obtained using the OR-based MDR.
rs10242595 | rs8178406 | Frequency (case:control) | OR (95% CI) |
---|---|---|---|
AA | CC | 17:5 | 2.80 (1.17–7.53) |
GA | CC | 42:44 | 0.79 (0.59–1.18) |
GG | CC | 28:32 | 0.72 (0.51–1.18) |
AA | TC | 48:54 | 0.73 (0.56–1.06) |
GA | TC | 136:124 | 0.90 (0.76–1.12) |
GG | TC | 108:94 | 0.95 (0.78–1.21) |
AA | TT | 32:33 | 0.80 (0.57–1.28) |
GA | TT | 132:71 | 1.53 (1.22–1.99) |
GG | TT | 77:53 | 1.20 (0.92–1.66) |
CI, confidence interval; MDR, multifactor-dimensionality reduction.
Bold values are significant results.