Table 2.

Details of association results with all genotyped SNPs in PPARD

					Allelicb					Haplotypicc
SNP	Location	Function	Alleles	MAFa	Informative Families	S	E(S)	Var(S)	p	2 SNP p	3 SNP p	4 SNP p
rs7744392	35430741	intron	A/G	0.048	31	31	22.5	18.25	0.0466	0.1588	0.1271	0.1770
rs9470001	35441719	intron	G/C	0.079	44	50	41.5	31.25	0.1284	0.1195	0.1689	0.0010
rs9658100	35464618	intron	T/G	0.08	44	52	42.5	34.25	0.1045	0.1421	0.0011	0.0008
rs6457816	35470826	intron	T/C	0.085	51	61	50.0	39.00	0.0782	0.0008	0.0004	0.0006
rs2267665	35477469	intron	G/A	0.155	94	58	89.5	75.25	0.0003	0.0010	0.0012	0.0036
rs2267666	35478706	intron	T/A	0.237	110	105	124.5	94.25	0.0446	0.0016	0.0052	0.0035
rs6906237	35483504	intron	C/A	0.073	44	52	40.5	31.25	0.0397	0.0029	0.0026	0.0041
rs2016520	35486756	5′ UTR	A/G	0.184	95	72	98.0	80.00	0.0037	0.0005	0.0012	0.0041
rs9462082	35494019	intron	G/A	0.143	86	48	79.5	67.25	0.0001	0.0003	0.0012	0.0020
rs2076169	35496457	intron	T/C	0.095	64	40	62.0	53.50	0.0026	0.0106	0.0132	0.0049
rs2076168	35497977	intron	A/C/T	0.201	98	81	102.5	76.25	0.0138	0.0268	0.0032	0.0096
rs2076167	35499765	synonymous	A/G	0.223	106	93	112.5	85.75	0.0352	0.0021	0.0062	0.0089
rs2076166	35501382	intron	C/T	0.137	88	50	78.0	67.00	0.0006	0.0040	0.0064
rs3734254	35502988	3′ UTR	T/C	0.187	100	88	108.5	84.25	0.0255	0.0051
rs1053046	35503556	3′ UTR	G/A	0.06	38	42	34.5	25.25	0.1356

^aMAF = Minor Allele Frequency

^bAllelic results from FBAT; statistics for the minor allele shown

^cHaplotypic results from HBAT; Results presented for 2-, 3-, and 4-SNP sliding window haplotypes. The p-value for each haplotype is listed in the row for the first SNP in the haplotype.