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. 2011 Aug 2;105(6):773–777. doi: 10.1038/bjc.2011.285

Table 3. Toxicities commonly observed (>20%) and grade 3–4 toxicities.

  All Patients (N=41)
Schedule B (N=22) Schedule A (N=19)
Adverse event All Grades Grades 3–4 Grades 3–4 Grades 3–4
Leukopaenia 8 (20%) 7 (17%) 4 (18%) 3 (16%)
Neutropaenia 19 (46%) 17 (41%) 11 (50%) 6 (32%)
Thrombocytopaenia 12 (29%) 5 (12%) 4 (18%) 1 (5%)
Nausea 21 (51%)
Fatigue 17 (41%)
Constipation 9 (22%)
Infusion site pain 9 (22%)