Table 3.
The targeting efficiency of Ty5 to HM loci in wild-type and Δsir strains
| Genotype
|
Chromosomal events characterized
|
Effective integration eventsa
|
Insertions near HM silencers
|
Percent HM targeting
|
Fold reduction in HM targeting
|
|---|---|---|---|---|---|
| Wild-type | 200 | 190 | 12 | 6.32 | N.A. |
| Δsir1 | 200 | 193 | 5 | 2.59 | 2.44 |
| Δsir2 | 210 | 175 | 3 | 1.71 | 3.70 |
| Δsir3 | 340 | 300 | 2 | 0.67 | 9.43 |
| Δsir4 | 230 | 84 | 0 | N.A. | N.A. |