Table 3.
Mutant
|
Allele
|
Phenotype
|
Gene
|
---|---|---|---|
Transcription | |||
not really finished | nrlhi399a | photoreceptor layer in eye dies | transcription factor (NRF-1b/IBRc) |
no arches | narhi1d | multiple defects, apoptosis | polyadenylation factore/RNasef |
Translation | |||
bubble brain | bbrhi10 | enlarged ventricle in brain | 60S ribosomal protein–L44g |
nearly normal | nanhi14 | ∼90% no swim bladder, ∼10% small adult | translation factor–EF1γn |
Other cell biology | |||
no knack | nokhi5 | edema, poor circulation | protein sorting factor–αNACi |
bleached blond | bblhi112 | pigment defects in eye and body | vacuolar ATP synthase, Ac45 subunitj |
Novel EST (expressed sequence tag) | |||
pescadillo | peshi2k | some organs smaller | BRCT mofitl |
not really started | nrshi891m | yolk degenerates | possible transporter |
dead eye | dyehi4k | CNS apoptosis | possible nuclear pore proteinn |
Hagoramo | HaghiD1,D2o | stripes interrupted in body region (dominant) | F-box/WD-40 repeat proteinp |
Not yet cloned | |||
hiD862 | long fins (dominant) | ||
hi37 | reduced head structures | ||
hi43 | liver defects | ||
hi61 | lethal | ||
hi63 | little head, no jaw | ||
hi96 | multiple edemas | ||
hi80A | multiple defects |
Becker et al. (1998); bEvans and Scarpulla (1990); cGomez-Cuadrado et al. (1995); dGaiano et al. (1996b); eBarabino et al. (1997); fBai and Tolias (1996); gDavies et al. (1986); hCormier et al. (1991); iWiedmann et al. (1994); jSupek et al. (1994); kAllende et al. (1996); lBork et al. (1997); mM. Allende, H. Wang, S. Marty, S. Lin, and N. Hopkins, (unpubl.); nGrandi et al. (1993); oK. Kawakami and N. Hopkins (unpubl.); pBai et al. (1996).