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. Author manuscript; available in PMC: 2012 Aug 11.
Published in final edited form as: J Med Chem. 2011 Jul 14;54(15):5307–5319. doi: 10.1021/jm200004e

Figure 4.

Figure 4

Dose-dependent suppression of T-cell response to type II collagen (CII) in vitro by peptide P6 in cells harvested from CII-primed from DQ8 mice, humanized transgenic mouse model of arthritis. In vitro T-cell response to CII was measured in the presence or absence of peptide 6 at four different concentrations. Change in counts per minute (cpm) was plotted to represent the T-cell proliferation. Delta cpm (Δcpm) was calculated by subtracting medium control from the test samples. The data show mean ±S.D. (N = 4).