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. Author manuscript; available in PMC: 2012 Aug 11.
Published in final edited form as: J Med Chem. 2011 Jul 14;54(15):5307–5319. doi: 10.1021/jm200004e

Table 1.

Sequence of peptides used in the study

Code Sequence Comments Purity
5 Cyclo (1,8) I1Y2D3(D)P4P5D6D7K8 (D)-Pro-Pro for β-hairpin, truncated form of 6 >95
6 Cyclo (1,10) S1I2Y3D4(D)P5P6D7D8I9K10 (D)-Pro-Pro for β-turn, S1-D4 to D7-K10 residues from CD2 protein sequence   95
7 Cyclo(1,6)K1D2D3-DBF-D4Y5I6 DBF for β-hairpin, sequence from protein CD2 used in anti-clockwise direction. Truncated form of 8 >95
8 Cyclo(1,8) K1I2D3D4-DBF-D5Y6I7S8 DBF for β-hairpin, sequence from protein CD2 used in anti-clockwise direction >95
9 Cyclo(1,6) I1Y2D3-DBF-D4D5K6 DBF for β-hairpin, sequence from protein CD2 used as it appears in protein. Truncated form of 10 >95
10 Cyclo(1,8) S1I2Y3D4-DBF-D5D6I7K8 DBF for β-hairpin, sequence from protein used as it appears in protein >95
C KGKTDAISVKAI-NH2 Control peptide. Sequence from hot-spot region was reversed, Tyr replaced by Ala. >95