Table 4. Adverse effects of mycophenolate mofetil monotherapy.

Adverse effects	No. affected (% of study population)	Ratea	95% CI
Any complication	29 (55.8)	0.32	0.22–0.46
GI disturbance	11 (21.2)	0.12	0.06–0.22
Fatigue	6 (11.5)	0.07	0.02–0.14
Leukopeniab	5 (9.6)	0.06	0.02–0.13
Pneumonia	2 (3.8)	0.02	0.003–0.08
Musculoskeletal pain	2 (3.8)	0.02	0.003–0.08
Headache	1 (1.9)	0.01	0.0003–0.06
Oral ulcer	1 (1.9)	0.01	0.0003–0.06
Mood swing	1 (1.9)	0.01	0.0003–0.06
Significant adverse effects reversed upon dosage decrease	4 (7.7)	0.04	0.01–0.11
Therapy discontinued because of significant reactions	6 (11.5)	0.07	0.02–0.14

Abbreviations: CI, confidence interval; GI, gastrointestinal.

^aDefined as number of events per person-year at risk.

^bDefined as WBC <3500/mm³.