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. 2011 Jan 21;25(4):502–510. doi: 10.1038/eye.2010.228

Table 4. Area under the ROC (AUC), P-value (P), 95% confidence interval of AUC, threshold (TH), sensitivity, and specificity.

  AUC P 95% Confidence interval TH Sensitivity Specificity
TMH 0.715 0.013 0.565 0.865 0.2 (ref. 66) 0.65 0.65
NIBUT 0.895 <0.001 0.791 1.000 10.0 (ref. 65) 0.80 0.93
Temporal LIPCOF 0.748 0.004 0.603 0.893 2 (ref. 19) 0.60 0.81
Nasal LIPCOF 0.828 <0.001 0.698 0.957 1 (ref. 19) 0.73 0.91
LIPCOF Sum 0.816 <0.001 0.687 0.945 2 (ref. 19) 0.70 0.81
Bulbar hyperaemia 0.664 0.057 0.501 0.827 2.35a
Limbal hyperaemia 0.509 0.914 0.341 0.678 2.05a
PRTT 0.781 0.001 0.642 0.919 10 (ref. 70) 0.25 0.93
Corneal staining 0.519 0.830 0.349 0.688 0.1a
Conjunctival staining 0.506 0.949 0.337 0.674 1.0a
LWE 0.749 0.004 0.597 0.901 1 (ref. 19) 0.48 0.96
Dry eye test combination 0.944 <0.001 0.865 1.024 −0.19a 0.90 0.89

Abbreviations: LIPCOF, lid-parallel conjunctival fold; LWE, lid-wiper epitheliopathy; NIBUT, non-invasive break-up time; PRTT, phenol red thread test; TMH, tear meniscus height.

a

Thresholds derived from this data set.