Table 4. Area under the ROC (AUC), P-value (P), 95% confidence interval of AUC, threshold (TH), sensitivity, and specificity.
AUC | P | 95% Confidence interval | TH | Sensitivity | Specificity | ||
---|---|---|---|---|---|---|---|
TMH | 0.715 | 0.013 | 0.565 | 0.865 | 0.2 (ref. 66) | 0.65 | 0.65 |
NIBUT | 0.895 | <0.001 | 0.791 | 1.000 | 10.0 (ref. 65) | 0.80 | 0.93 |
Temporal LIPCOF | 0.748 | 0.004 | 0.603 | 0.893 | 2 (ref. 19) | 0.60 | 0.81 |
Nasal LIPCOF | 0.828 | <0.001 | 0.698 | 0.957 | 1 (ref. 19) | 0.73 | 0.91 |
LIPCOF Sum | 0.816 | <0.001 | 0.687 | 0.945 | 2 (ref. 19) | 0.70 | 0.81 |
Bulbar hyperaemia | 0.664 | 0.057 | 0.501 | 0.827 | 2.35a | — | — |
Limbal hyperaemia | 0.509 | 0.914 | 0.341 | 0.678 | 2.05a | — | — |
PRTT | 0.781 | 0.001 | 0.642 | 0.919 | 10 (ref. 70) | 0.25 | 0.93 |
Corneal staining | 0.519 | 0.830 | 0.349 | 0.688 | 0.1a | — | — |
Conjunctival staining | 0.506 | 0.949 | 0.337 | 0.674 | 1.0a | — | — |
LWE | 0.749 | 0.004 | 0.597 | 0.901 | 1 (ref. 19) | 0.48 | 0.96 |
Dry eye test combination | 0.944 | <0.001 | 0.865 | 1.024 | −0.19a | 0.90 | 0.89 |
Abbreviations: LIPCOF, lid-parallel conjunctival fold; LWE, lid-wiper epitheliopathy; NIBUT, non-invasive break-up time; PRTT, phenol red thread test; TMH, tear meniscus height.
Thresholds derived from this data set.