Table 4.

Rank and p value of the 4 pancreatic cancer-associated SNPs from analyses with varying numbers of additional controls

SNP/odds ratio/minor allele frequency		Control:case ratio
		1:1	5:1	10:1	20:1
rs505922/	rank	105,668	6,769	5,302	216
1.2/	p value	0.393	0.02	0.01	0.0007
0.358	power	0.20	0.33	0.349	0.364
rs9543325/	rank	477	21	72	52
1.26/	p value	0.0019	8.2 × 10−5	2.5 × 10−4	1.6 × 10−4
0.317	power	0.29	0.48	0.50	0.53
rs3790844/	rank	102,024	7,645	1,977	1,357
0.77/	p value	0.38	0.02	0.007	0.004
0.21	power	0.265	0.49	0.51	0.53
rs401681/	rank	265,649	239,819	152,561	157,875
1.19/	p value	0.99	0.91	0.57	0.58
0.434	power	0.198	0.313	0.32	0.347

Correction for population stratification is performed in all analyses. Analytical power is computed assuming an additive model with α = 0.05.