Table 1.
All n = 508 |
Below targetΔ n = 58 |
Above targetΔ n = 450 |
|
---|---|---|---|
Age (years) | 63 (50-73) | 55 (45-71) | 64 (50-73) |
Sex (% men) | 57 | 57 | 56 |
Caucasian (%) | 97 | 97 | 96 |
BMI (kg/m2)* | 26 ± 5 | 25 ± 4 | 26 ± 5 |
Smokers/quitters < 1 year before inclusion (%) | 56 | 50 | 57 |
Primary kidney disease (%) | |||
Diabetes mellitus | 17 | 16 | 17 |
Glomerulonephritis | 10 | 14 | 9 |
Interstitial nephritis | 16 | 17 | 15 |
Renal vascular disease/nephrosclerosis | 23 | 17 | 23 |
Baseline eGFR (ml/min/1.73 m2)† | 13.1 ± 5.8 | 14.0 ± 6.0 | 13.0 ± 5.7 |
Proteinuria (g/24 h)‡ | 2.0 (0.7-3.9) | 1.1 (0.6-2.9) | 2.2 (0.8-4.0) |
Hemoglobin (g/dl)§ | 11.3 ± 1.6 | 11.4 ± 1.8 | 11.3 ± 1.6 |
Co-morbidities (%) | |||
Anemia· | 47 | 46 | 47 |
Cardiovascular diseaseγ | 36 | 28 | 37 |
Diabetes mellitus | 27 | 24 | 27 |
Malignancy | 11 | 10 | 11 |
Referral to pre-dialysis care by nephrologist (%) | 76 | 78 | 76 |
Median with boundaries of interquartile range (IQR) is given for age and proteinuria and for the other continuous variables mean ± standard deviation (SD) is given. Δ Below the target was defined as SBP < 130 and DBP < 80 mmHg and above the target as SBP ≥ 130 and/or DBP ≥ 80 mmHg. * Available for 472 patients. † estimated glomerular filtration rate (eGFR) calculated with the abbreviated Modification of Diet in Renal Disease (MDRD) formula and available for 445 patients. ‡ Available for 405 patients. § Available for 444 patients. · Defined as a hemoglobin level < 11 g/dl. γ Defined as the presence of angina pectoris, coronary disease, and/or myocardial infarction.