Figure 3.

unc-4 mutations. (A) Approximate locations of UNC-4 point mutations. (HD) Homeodomain; (eh1) Engrailed-like repressor domain. (B) unc-4 frameshifts and deletions. Vertical bars denote EcoRI sites; boxes represent unc-4 exons; solid boxes show exons encoding the homeodomain (exon five contains the eh1 domain); shaded overlays denote deleted regions. Arrowheads indicate splice donor site mutations in e120 and jd16. Large open rectangles around e2320, e120, and jd16 exons denote frameshifted coding sequence.