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UNC-37(E580K) suppresses specific unc-4 missense mutations
| Allele
|
Mutation
|
Suppresseda
|
|---|---|---|
| e2322ts | L121F | + |
| e26 | G188D | − |
| e2307 | G188S | − |
| e2323 | R190Q | + |
| e521 | R197K | + |
| e2321 | R197K | + |
| wdEx65 | F174E | − |
| wd44 | W20-stop | − |
| e2309 | W98-stop | − |
| e583 | Q137-stop | − |
| jd16 | splice donor site mutation | − |
| e120 | splice donor site mutation | − |
| e887 | deletion | − |
| e2320 | deletion | − |
| wd1 | deletion | − |
(+) unc-4 alleles that are suppressed by UNC-37 (E580K); (−) nonsuppressed unc-4 mutations.
