Table 3. Relationship between weighted GRS as groups and as continuous and age at RA symptom start.
| Mean Agea (95% CI) | |||
| GRS39 Group | Seropositive (n = 317) | Erosive RA (n = 163) | Sero+ Erosive RA (n = 105) |
| 1 | 51.1 (46.5–55.7) | 52.3 (46.5–58.1) | 42.3 (37.6–53.0) |
| 2 | 57.4 (53.7–61.2) | 55.1 (49.6– 60.6) | 55.8 (44.8–66.8) |
| 3 | 55.3 (53.2–57.4) | 54.5 (51.2–57.8) | 56.3 (52.6–60.1) |
| 4 | 56.8 (54.7–58.9) | 54.8 (51.7–58.0) | 53.2 (48.1–58.2) |
| 5 | 54.8 (52.6–57.0) | 51.5 (48.0–55.0) | 49.9 (45.7–54.1) |
| 6 | 53.5 (51.0–56.0) | 51.7 (47.8–55.6) | 50.6 (46.5–54.8) |
| 7 | 55.2 (53.5–56.8) | 54.0 (51.6–56.3) | 52.7 (50.2–55.2) |
| total | 55.3 (54.1–56.4) | 53.5 (51.9–55.2) | 52.6 (50.6–54.5) |
| ρ b | −0.090 | −0.078 | −0.109 |
| p-value | 0.109 | 0.325 | 0.268 |
a
adjusted for year of birth and pack-years of smoking,
b
ρ = Pearson correlation coefficient comparing continuous age at RA symptom onset and continuous GRS.