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. 2011 Sep 12;6(9):e24682. doi: 10.1371/journal.pone.0024682

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Kye et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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(A–C) Up-regulated mature miRNAs have unchanged pri-miRNA levels. (D, E) Down-regulated mature miRNAs showing relatively unchanged pri-miRNA levels, (F) Both mature and pri-miRNA levels are down-regulated (G, H) Only pri-miRNAs are up-regulated (I) Both mature and pri-miRNAs are not changed after fear conditioning (FC). (* p<0.05, Man-Whitney test, home cage: n = 12, 1 h and 3 h: n = 12, 24 h: n = 8, mean ± S.E.M.).