Table 1.
Placental gene expression assayed by in situ hybridization of E8.5 and E9.5 embryos
| Decreased expression
|
Expressing cells
|
|---|---|
| TGFβ3 | giant cells |
| Unaltered expression | |
| TGFβ1 | all trophoblasts |
| Glucose transporter-1 | all trophoblasts |
| Glucose transporter-3 | all trophoblasts |
| Mash 2 | all trophoblasts |
| tissue factor | all trophoblasts |
| p21 | all trophoblasts |
| Tfeb | labyrinthine trophoblasts |
| PDGFβ | spongiotrophoblasts |
| PDGFRβ | spongiotrophoblasts |
| VEGF | giant cells |
| proliferin | giant cells |
| proliferin-related protein | giant cells |
| placental growth factor | giant cells |
| CSF-1R | giant cells |
| Tie-2 | endothelial cells |
This table takes into account the changes in 4311+ spongiotrophoblast and Pl. Lac. 1+ giant cell numbers in Arnt−/− placentas and reflects expression of each listed gene in individual cells.