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. 2011 Aug 30;17:2333–2342.

Figure 2.

Figure 2

Representative images of slit-lamp photographs and 1310 nm time-domain optical coherence tomography scans of patients with lattice corneal dystrophy type I (family F1); lattice corneal dystrophy variants (families F2 and F7). There is a noticeable phenotypic heterogeneity between corneal morphology of lattice corneal dystrophy variants caring the same H626R mutation. A: Male patient (F1; 37 years). Slit-lamp retroillumination photograph showing diffuse multiple lattice lines. LCDI/R124C mutation. B: Male patient (F1; 37 years). High-resolution corneal scan – 1310 nm time. domain OCT. There is a diffuse border between the anterior part of increased reflectivity and normal corneal stroma (arrowheads). The areas of increased stromal reflectivity correspond with corneal opacities. LCDI/R124C mutation. C: Female patient (F2; 45 years). Slit-lamp photograph. Delicate, fragile, rare lattice lines located centrally. LCD variant/ H626 mutation. D: Female patient (F2; 45 years). High-resolution corneal scan – 1310 nm time. domain OCT. Opacities with increased reflectivity visible through the whole depth of the cornea. Some of the opacities are located in the posterior corneal part (arrows). LCD variant/H626 mutation. E: Female patient (F7; 48 years). Slit-lamp photograph. Thick, distinct lines accompanied by stromal haze extended from limbus to limbus. LCD variant/H626 mutation. Note the distinct heterogeneity compared to Figure 2C. F: Female patient (F7; 48 years). High-resolution corneal scan – 1310 nm time. domain OCT. Opacities with increased reflectivity located mainly in the posterior corneal part causing distortion of the posterior corneal surface. LCD variant/H626 mutation.